What adjustments are necessary to make a 100-year life meaningful at every stage?
By the middle of this century, it will be commonplace for people to live to be 100 years old. This continues a remarkable trend that has led to a doubling of human life expectancy over the last century—faster than ever before in the history of human evolution. In the Western world, half of today’s five-year-olds can expect to live to 100, and by 2050, this could become the norm for newborns.
However, our social institutions, norms, and policies were developed at a time when life was only half as long, and therefore they need to be updated. The Stanford Center on Longevity has launched an initiative that recognizes that this profound change in the human experience will also require significant and creative adjustments to make these 100-year lives meaningful at every stage. The challenges of longevity can be overcome if we act now and are guided by these principles.
Making the most of the 100-year opportunity
The New Map of Life challenges us to look beyond the negative aspects of aging, such as health problems, mobility limitations, or financial insecurity, and consider the contributions older adults make to society in order to arrive at a true balance sheet of the costs and benefits of our current population structure.
Investing in future centenarians brings great returns
We can invest in the centenarians of tomorrow by optimizing each stage of life so that benefits accumulate over decades and we have more time to recover from setbacks and adversity. The crucial years between birth and kindergarten are the best time for children to acquire many of the cognitive, emotional, and social skills necessary for a healthy, happy, and active life.
Aligning healthspan with lifespan
A central principle of the New Map of Life is that a healthy long life requires investment in public health at every stage of life and that the health span should be the yardstick for how, when, and where to invest. Eliminating health inequalities requires investing not only in better access to health care, but also in the health of communities, especially those affected by poverty, discrimination, and environmental degradation.
Let’s be surprised by the future of aging
Today’s 5-year-olds will benefit from an amazing array of medical advances and new technologies that will make their experience of aging very different from that of today’s older adults. While the aging process cannot be stopped, the emerging field of geroscience has the potential to change the way we age by seeking to identify and “reprogram” the genetic, molecular, and cellular mechanisms that make age the dominant risk factor for certain diseases and degenerative conditions.
ÜTransitions in life are an advantage, not a disadvantage
While the traditional life course is a one-way street with prescribed stages, the new life map offers multiple routes that connect the roles, opportunities, and obligations of a 100-year life, and people are expected to reset their GPS again and again. The map offers more opportunities for informal and lifelong learning, as well as intergenerational partnerships that improve the flow of knowledge, support, and care in all directions.
Lifelong learning
Rather than limiting formal education to the first two decades of life, the new life map offers new opportunities for learning outside the confines of formal education, allowing people of all ages to acquire the knowledge they need at every stage of their lives and in a way that suits their needs, interests, abilities, schedules, and budgets.
Working longer and more flexibly
Over the course of a 100-year life, we will likely work for 60 years or more. But we will no longer work as we do today, squeezing 40-hour weeks into a life filled from morning to night with parenting, family, caregiving, school, and other commitments. Workers want flexibility, whether it’s working from home part of the time or having flexible hours, including paid and unpaid breaks for caregiving, health needs, lifelong learning, and other transitions that are to be expected over the course of a lifetime.
Financial security from the start
Financing a 100-year life requires new forms of work, savings, and retirement. It also requires new policies that respond to today’s economic realities: working life has become more uncertain, family structures are more diverse than in previous generations, and many people have little or no retirement savings. The new life map aims to offer more opportunities and starting points for building financial security by placing individual actions in a larger social and economic context.
Building sustainable communities
The influence of the physical environment begins even before birth. The advantages and disadvantages accumulate over the course of a lifetime and determine how likely a person is to be physically active, whether they are isolated or socially engaged, and how likely they are to suffer from obesity, respiratory, cardiovascular, or neurodegenerative diseases. We must start now to plan and build neighborhoods that are equipped for long life and evaluate potential investments in infrastructure from the perspective of longevity.
Age diversity is an asset to society
The dynamism, energy, and spirit of discovery of younger people, coupled with the emotional intelligence and wisdom of older people, create opportunities for families, communities, and workplaces that did not exist before. Instead of anxiously focusing on the costs of an “aging” society, the remarkable benefits of a truly age-diverse society should be measured and reaped.
The path to the future
Meeting the challenges of longevity is not the sole responsibility of governments, employers, healthcare providers, or insurance companies; it is a task that concerns everyone and requires the best ideas from the private sector, government, medicine, science, and philanthropy. It is not enough to redesign or rethink society to prepare it for long life; it must be built, and quickly. The policies and investments made today will determine how today’s young people become tomorrow’s elderly—and whether we make the most of the 30 extra years of life we have been given.
Vitality through exercise
How regular activity influences and improves lifespan
The link between exercise and longevity is a well-established and scientifically proven concept that highlights the profound impact of physical activity on extending a person’s lifespan and overall quality of life. Numerous studies and research findings have repeatedly shown that regular exercise is associated with a range of physiological, cellular, and molecular changes that contribute to longer life expectancy. The following section highlights the mechanisms underlying this relationship and how physical exercise influences the aging process.
Alleviation of chronic diseases
Regular physical activity plays a crucial role in the prevention and treatment of a number of chronic diseases that are closely linked to premature mortality. Diseases such as cardiovascular disease, type 2 diabetes, high blood pressure, and obesity contribute significantly to a reduction in life expectancy. Physical activity helps regulate blood pressure, cholesterol, and blood sugar levels, which are crucial for maintaining heart health and metabolic balance. By controlling these risk factors, physical activity significantly reduces the likelihood of developing these diseases and thus prolongs life expectancy.
Improving cardiovascular health
A strong cardiovascular system is important for overall health and longevity. Aerobic activities such as running, swimming, and cycling increase heart function, improve blood circulation, and strengthen blood vessels. Regular cardiovascular exercise contributes to a lower resting heart rate, improved cardiac output, and increased oxygen supply to tissues, which supports long-term heart health and extends life expectancy.
Promoting metabolic health
Physical activity has a profound effect on metabolism. It increases the body’s energy expenditure, helping to control weight and prevent obesity, which is associated with an increased risk of various diseases. Physical activity also improves insulin sensitivity, helping to regulate blood sugar levels and reduce the risk of insulin resistance, a precursor to diabetes. Maintaining a healthy metabolism is a crucial factor in living a long life.
Fighting inflammation
Chronic inflammation is a feature of many age-related diseases, including arthritis, cardiovascular disease, and neurodegenerative diseases. Regular physical exercise has been shown to modulate the body’s inflammatory response by lowering levels of pro-inflammatory markers. By reducing chronic inflammation, exercise helps create an environment in the body that is less conducive to the development and progression of inflammation-related diseases, contributing to a longer and healthier life.
Maintaining muscle mass and bone density
Aging is often accompanied by a loss of muscle mass and bone density, leading to frailty and an increased risk of falls and fractures. Resistance training and strength training help counteract this loss by stimulating muscle growth and strengthening bones. Maintaining muscle mass and bone density is crucial for preserving mobility, independence, and overall vitality in old age.
Improving cognitive function
Fitness is not only good for the body, but also has a significant impact on brain health. Regular physical activity has been shown to boost cognitive function, improve memory, and reduce the risk of cognitive decline and neurodegenerative diseases such as Alzheimer’s. The release of neurotrophic factors during exercise promotes the growth and maintenance of brain cells, contributing to better mental health and longevity.
Stress reduction and mental well-being
Physical activity triggers the release of endorphins, often referred to as “feel-good” chemicals. These endorphins promote a positive mood, reduce stress, and alleviate symptoms of anxiety and depression. Mental well-being is an essential part of overall health, and the effects of exercise on mental health and resilience have a direct impact on the ability to live a longer and more fulfilling life.
Telomere preservation
Telomeres are protective caps at the ends of chromosomes that naturally shorten with age. Shortened telomeres are associated with cellular aging and an increased risk of age-related diseases. Research suggests that regular physical activity may help maintain telomere length, slow cellular aging, and promote longevity.
In summary, the link between physical activity and longevity can be attributed to the diverse effects that exercise has on various physiological, cellular, and molecular processes in the body. By reducing chronic diseases, improving cardiovascular health, enhancing metabolic functions, combating inflammation, maintaining muscle mass and bone density, promoting cognitive function, reducing stress, and preserving telomeres, physical activity creates the conditions for a longer and healthier life. A regular exercise program tailored to individual abilities and preferences is an effective investment in one’s own well-being and the key to realizing the potential for a vital and fulfilling life into old age.
References
- Myers, J., Prakash, M., Froelicher, V., Do, D., Partington, S., & Atwood, J. E. (2002). Exercise capacity and mortality among men referred for exercise testing. New England Journal of Medicine, 346(11), 793-801.
- Gibala, M. J., Little, J. P., Macdonald, M. J., & Hawley, J. A. (2012). Physiological adaptations to low-volume, high-intensity interval training in health and disease. The Journal of Physiology, 590(5), 1077-1084.
- Park, S. Y., Son, W. M., & Kwon, O. S. (2016). Effects of whole body vibration training on body composition, skeletal muscle strength, and cardiovascular health. Journal of Exercise Rehabilitation, 12(6), 573-578.
- Murphy, M. H., Blair, S. N., & Murtagh, E. M. (2009). Accumulated versus continuous exercise for health benefit: a review of empirical studies. Sports Medicine, 39(1), 29-43.
- Thompson, P. D., Buchner, D., Piña, I. L., Balady, G. J., Williams, M. A., Marcus, B. H., … & Wenger, N. K. (2003). Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease. Circulation, 107(24), 3109-3116.
- Warburton, D. E., Nicol, C. W., & Bredin, S. S. (2006). Health benefits of physical activity: the evidence. Canadian Medical Association Journal, 174(6), 801-809.
- Fox, K. R. (1999). The influence of physical activity on mental well-being. Public Health Nutrition, 2(3a), 411-418.
- Nieman, D. C., & Wentz, L. M. (2019). The compelling link between physical activity and the body’s defense system. Journal of Sport and Health Science, 8(3), 201-217.
- Booth, F. W., Roberts, C. K., & Laye, M. J. (2012). Lack of exercise is a major cause of chronic diseases. Comprehensive Physiology, 2(2), 1143-1211.
- Hahm, J. H., Kim, S., DiLoreto, R., Shi, C., Lee, S. J., Murphy, C. T., & Nam, H. G. (2015). C. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation. Nature Communications, 6, 8919.
- Arem, H., Moore, S. C., Patel, A., Hartge, P., Berrington de Gonzalez, A., Visvanathan, K., … & Matthews, C. E. (2015). Leisure time physical activity and mortality: a detailed pooled analysis of the dose-response relationship. JAMA Internal Medicine, 175(6), 959-967.
- Sofi, F., Valecchi, D., Bacci, D., Abbate, R., Gensini, G. F., Casini, A., & Macchi, C. (2011). Physical activity and risk of cognitive decline: a meta-analysis of prospective studies. Journal of Internal Medicine, 269(1), 107-117.
- Lee, D. H., Lavie, C. J., & Vedanthan, R. (2019). Optimal dose of running for longevity: is more better or worse? Journal of the American College of Cardiology, 73(20), 2634-2636.
- Stamatakis, E., Lee, I. M., Bennie, J., Freeston, J., Hamer, M., O’Donovan, G., … & Tipton, K. (2018). Does strength promoting exercise confer unique health benefits? A pooled analysis of data on 11 population cohorts with all-cause, cancer, and cardiovascular mortality endpoints. American Journal of Epidemiology, 187(5), 1102-1112.
- Kekäläinen, T., Kokko, K., Sipilä, S., & Walker, S. (2019). Effects of a 9-month resistance training intervention on quality of life, sense of coherence, and depressive symptoms in older adults: randomized controlled trial. Quality of Life Research, 28(3), 767-776.
- Fox, F., Liu, D., Breteler, B., Aziz, N. (2023). Physical activity is associated with slower epigenetic ageing–Findings from the Rhineland study. Aging Cell, doi 10.1111 acel.13828.